Animal Ocular Toxicity Studies Through Ocular Delivery

Introduction The ocular drug development landscape is rapidly expanding, encompassing small molecules, biologics, gene and cell therapies, and novel drug delivery platforms. Increasingly, ocular delivery routes such as intravitreal, subconjunctival, and periocular administration are being used to target the posterior segment of the eye and support the development of injectable and implantable prolonged-action dosage forms….

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Frozen for 46,000 Years, This Siberian Worm Came Back to Life

Scientists have revived a microscopic organism that remained frozen for approximately 46,000 years in Siberian permafrost, an achievement that is redefining scientific understanding of survival, dormancy, and the limits of life itself. Recovered from Pleistocene-era sediments near the Kolyma River, the revived worm resumed movement and feeding shortly after thawing, behaving as though its tens…

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